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Minoxidil

Product Name: Minoxidil
Synonyms: 2, 4 – diamino – 6 – piperidinopyrimidine3 – n – oxide; 4-pyrimidinediamine,6-(1-piperidinyl)-3-oxide; – amino – 1, 2, 6 – dihydro – 1-2 – imino – 4 – hydroxy – piperidinopyrimidine; 6 – piperidino – 2, 4 – diaminopyrimidine3 – oxide; alopexil; 4 – (2, 6 – diamino – piperidin – 1 – yl) -ium pyrimidin – 1-1 – olate; alostil; lonolox
CAS: 38304-91-5
MF: C9H15N5O
MW: 209.25
EINECS: 253-874-2
Product Categories: Cardiovascular drugs; Antihypertensive class; Hormones; Hair care series; Circulatory system medication; Pharmaceutical intermediate; Vitamins and amino acids; Antibiotics; Small molecule inhibitor; Chemical raw materials; Raw material intermediates – apis; Hypoglycemic products; Chemical intermediates
Introduction Minoxidil, also known as minoxidil, is a white or quasi-white crystalline powder, slightly soluble in water or chloroform, slightly soluble in ethanol. It can directly act on the blood vessel wall, expand small arteries, reduce peripheral resistance, and decrease blood pressure. It can also increase heart rate and cardiac output, but its antihypertensive effect is more significant and lasting than hydralazine
Application Antihypertensive drugs for refractory, primary, or renal hypertension.

Used to prevent greasy alopecia and animal husbandry.

Minoxidil Chemical Properties
Melting point 272-274 °C (dec.) (lit.)
Boiling point 348.61°C (rough estimate)
Density 1.1651 (rough estimate)
Refractive index 1.7610 (estimate)
storage condition 2-8°C
Solubility Slightly soluble in water, soluble in methanol and in propylene glycol.
Water solubility Soluble in water (2.2 mg/ml), 100% ethanol (29 mg/ml), propylene glycol, acetone, DMSO (6.5 mg/ml), and methanol.
form Powder
color White crystal
pKa 4.61(at 25℃)

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