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Compound 7P CAS 1890208-58-8
| Product Name: | Compound 7P |
| Synonyms: | Compound 7P;Acetamide, 2-[(2-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)- |
| CAS: | 1890208-58-8 |
| MF: | C22H23N3O5S |
| MW: | 441.5 |
| EINECS: | 200-184-4 |
| Mol File: | 1890208-58-8.mol |
| Introduction | Compound 7p was shown to induce growth of gap-43 positive axons, indicating that the in vitro neurite outgrowth activity of compound 7p translates into stimulation of axon regeneration in vivo.further optimization of compound 7p and elucidation of the mechanisms by which it elicits axon regeneration in vivo will provide a rational basis for future efforts to enhance treatment strategies. enhances neurite outgrowth in cultured primary neurons derived from the hippocampus, cerebral cortex, and retina and that induces optic nerve regeneration in an animal model of optic nerve injury. Although it needs to be determined how the compound stimulates axon growth in vivo, our results should provide further insight into the treatment strategies for clinical conditions associated with a loss of axon. |
| Compound 7P Chemical Properties | |
| density | 1.329±0.06 g/cm3(Predicted) |
| pKa | 11?+-.0.70(Predicted) |
| form | Crystalline powder |
| color | white |
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