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LY2456302 / Aticaprant CAS 1174130-61-0

Product Name: LY2456302;Aticaprant
Synonyms: (S)-4-(4-((2-(3,5-diMethylphenyl)pyrrolidin-1-yl)Methyl)phenoxy)-3-fluorobenzaMide;LY2456302;LY2456302;LY2456302;CERC501;CERC501;CS-2732;CERC-501(LY-2456302,Aticaprant);Aticaprant;Benzamide,4-[4-[[(2S)-2-(3,5-dimethylphenyl)-1-pyrrolidinyl]methyl]phenoxy]-3-fluoro-;4-[4-[[(2S)-2-(3,5-Dimethylphenyl)-1-pyrrolidinyl]methyl]phenoxy]-3-fluorobenzamide
CAS: 1174130-61-0
MF: C26H27FN2O2
MW: 418.5
Product Categories: /
Mol File: 1174130-61-0.mol
Introduction This small molecule drug is a κ-opioi receptor (KOR) antagonist.  Its molecular formula is C26H26FN2O2, its molecular weight is 418.5, and its CAS number is 1174130-61-0. It is a highly effective KOR antagonist that can penetrate the central nervous system, with a Ki value of 0.807 nM.
Aticaprant Chemical Properties
Boiling point 519.2±50.0 °C(Predicted)
Density 1.201±0.06 g/cm3(Predicted)
Storage conditions Store at -20°C
Solubility DMF: 1mg/mL; DMSO: 5mg/mL; Ethanol: 3mg/mL; PBS (pH 7.2) : Insoluble
pKa 15.61±0.50(Predicted)
color White to off-white

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