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(S)-3-Hydroxy-gamma-butyrolactone CAS 7331-52-4

(S)-3-Hydroxy-gamma-butyrolactone Basic information
Product Name: (S)-3-Hydroxy-gamma-butyrolactone
Synonyms: 2(3H)-FURANONE,DIHYDRO-3-HYDROXY-,(S);2(3H)-FURANONE,DIHYDRO-4-HYDROXY-,(S);(S)-4-HYDROXYTETRAHYDROFURAN-2-ONE;(S)-4,5-DIHYDRO-4-HYDROXY-2(3H)-FURANONE;(S)-(-)-3-HYDROXYBUTYROLACTONE;(S)-3-HYDROXYBUTYROLACTONE;(S)-(-)-3-HYDROXY-GAMA-BUTYROLACTONE;(S)-(-)-3-HYDROXY-GAMMA-BUTYROLACTONE
CAS: 7331-52-4
MF: C4H6O3
MW: 102.09
EINECS: 434-990-4
Product Categories: Chiral compounds; Tetrahydrofuran series; Pharmaceutical intermediates; Organic building blocks; General reagents; chiral; TetrahydrofuranSeries; Intermediate of ezetimibe; ChiralBuildingBlocks; SimpleAlcohols(Chiral); SyntheticOrganicChemistry; Esters; Chemical raw materials; Pharmaceutical raw materials
Mol File: 7331-52-4.mol
Introduction (S) 3-hydroxy-gamma-butyrolactone, also known as (S) -3-hydroxy – γ – butyrolactone, is an important chiral source compound that can be prepared from L-malic acid as a raw material. This substance is a synthetic raw material for various drug molecules and can also be used in the study of drug metabolites.
Application Used as an intermediate in organic synthesis
(S)-3-Hydroxy-gamma-butyrolactone Chemical Properties
Boiling point 98-100 °C0.3 mm Hg(lit.)
Density 1.241 g/mL at 25 °C(lit.)
refractive index n20/D 1.464(lit.)
flash point >230 °F
Acidity coefficient (pKa) 12.87±0.20(Predicted)
Water solubility Miscible with water, alcohol and other organic solvent. Immiscible with light petroleum.
Optical Rotation [α]21/D 81°, c = 2 in ethanol
Storage Inert atmosphere,2-8°C
color Brown to reddish brown liquid

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