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CMS121 CAS 1353224-53-9
| Product Name: | 4-(4-(cyclopentyloxy)quinolin-2-yl)benzene-1,2-diol |
| Synonyms: | CMS-121;1,2-Benzenediol,4-[4-(cyclopentyloxy)-2-quinolinyl]-;4-(4-(cyclopentyloxy)quinolin-2-yl)benzene-1,2-diol(CMS121);ACC,AcetylCoenzymeACarboxylase,disease,neuroprotective,inhibit,anti-inflammatory,mitochondrial,Alzheimer’s,antioxidative,acetylation,Inhibitor,H3K9,Acetyl-CoACarboxylase,CMS121,dementia,ACC1,CMS-121;CMS-121,10mMinDMSO;4-(4-(cyclopentyloxy)quinolin-2-yl)be |
| CAS: | 1353224-53-9 |
| MF: | C20H19NO3 |
| MW: | 321.37 |
| Product Categories: | Drug molecules, organic intermediates, and organic raw materials. |
| Mol File: | 1353224-53-9.mol |
| Introduction | CMS-121 is a quinolone derivative and an orally active acetyl CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells from ischemia and oxidative damage with EC50 values of 7nM and 200nM, respectively. CMS-121 has strong neuroprotective, anti-inflammatory, antioxidant, and renal protective effects. |
| CMS121 Chemical Properties | |
| Boiling point | 511.0±50.0 °C(Predicted) |
| Density | 1.297±0.06 g/cm3(Predicted) |
| Acidity coefficient (pKa) | 8.53±0.20(Predicted) |
| Storage | Store at -20°C |
| form | Crystalline solid |
| color | Light yellow to yellow |
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