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Elamipretide
| Product Name: | Elamipretide |
| Synonyms: | D-Arginyl-2,6-diMethyl-L-tyrosyl-L-lysyl-L-phenylalaninaMide;Elamipretide;Centanafadine;L-Phenylalaninamide,D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-;Elamipretide(TFAsalt);SS-31;MTP-131;BENDAVIA;Bendavia);Elamipretide(SS-31 |
| CAS: | 736992-21-5 |
| MF: | C32H49N9O5 |
| MW: | 639.79 |
| EINECS: | 205-858-1 |
| Product Categories: | Peptide intermediates; Drug peptides; Drug peptides |
| Mol File: | 736992-21-5.mol |
| Introduction | Elamipretide (MTP-131, SS-31, D-Arg-Dmt-Lys-Phe-NH2) is an inhibitor of cytochrome c peroxidase. Elamipretide can improve mitochondrial dysfunction, synaptic and memory impairments induced by lipopolysaccharide in mice. |
| Application | Elamipretide acetate is a small molecule peptide composed of four amino acids. In vivo, Elamipretide targets the inner membrane of mitochondria and can prevent oxidative damage to nerve cells and other cell types; Prevent mitochondrial depolarization, reduce pancreatic cell apoptosis, increase pancreatic cell production, and improve post transplant function. |
| Elamipretide Chemical Properties | |
| Density | 1.34±0.1 g/cm3(Predicted) |
| Acidity coefficient (pKa) | 10.10±0.25(Predicted) |
| solubility | Methanol (slightly soluble), water (slightly soluble) |
| form | solid |
| color | White to off white |
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